What is a potential result of untreated tertiary syphilis?

Tertiary syphilis is a serious stage of syphilis infection that can occur years after the initial infection if left untreated. One of the hallmark potential results of untreated tertiary syphilis is neurological degeneration. This occurs due to the involvement of the central nervous system, which can lead to a variety of neurological symptoms such as dementia, ataxia, or even paralysis. The condition known as tabes dorsalis is a specific manifestation where the dorsal columns of the spinal cord are damaged, resulting in loss of proprioception and joint sense.

The severe consequences of tertiary syphilis underline the importance of early detection and treatment of syphilis. Appropriate antibiotic therapy during earlier stages can prevent the progression to this advanced and life-altering phase of the disease, which can also involve other organ systems leading to cardiovascular issues, gummatous lesions, and more. Understanding these potential outcomes emphasizes the seriousness of the infection and the need for effective public health measures to combat syphilis.